Can Low-Fat Be Salvaged? – Updated WHI Dietary Modification Trial Results

A recent paper published in the American Journal of Clinical Nutrition provides updated results from the Women’s Health Initiative (WHI) Dietary Modification Trial (1). One of the questions raised is whether there is still hope for a low-fat dietary approach for the prevention of heart disease. The primary aim of the WHI Dietary Modification Trial was to … Read more

From Low-Fat, High-Carb to Insulin Resistance, Fatty Liver, and Heart Disease

I recently gave a talk at a meeting with colleagues, most of them cardiologists and endocrinologists, where I, among other things, discussed the current status of diet-heart hypothesis and the possible relationship between our fear of dietary fats and the obesity epidemic. After the meeting, a senior colleague of mine, an old friend, and a … Read more

Less Heart Disease Despite More Diabetes; The Role of Diet

The diverging trends in heart disease and diabetes represent a public health paradox of immense importance. Obesity and type 2 diabetes are well-known risk factors for coronary heart disease. However, whereas the prevalence of obesity and type 2 diabetes is increasing, the death rate from coronary heart disease is declining. This interesting paradox was recently addressed in two … Read more

The Road to Diabetes and Heart Disease – The “Ticking Clock” Hypothesis

One of the key reasons we do not want to get diabetes is that we will be more likely to be hit by heart disease or stroke or even Alzheimer’s disease for that matter. It’s scientifically proven. Having diabetes is associated with an increased risk of getting these disorders. But, does diabetes cause heart diseases or stroke? Hmm, … Read more

Which Is Most Atherogenic, High-Fat Cheese, High-Fat Meat or Carbs?

Atherosclerosis is the most common underlying cause of cardiovascular disease (CVD. It is caused by a complex interplay between lipoproteins, white blood cells, the immune system and the normal elements of the arterial wall. Atherosclerosis can affect all arteries in the body but seems to have a strong affinity for the coronary arteries. The resulting … Read more