Because Good Medicine Deserves Better Explanations
When to prescribe statin therapy for people without established cardiovascular disease is a hotly debated issue among medical doctors. Recent clinical guidelines have recommended extending the use of these drugs to reduce the burden of cardiovascular disease. Recommendations on statin use are to a large extent based on meta-analyses on data from randomized controlled trials, either comparing statins to placebo … Read more
Recently, concerns have been raised about the increased risk of diabetes associated with statin therapy. However, it has been pointed out that the risk of diabetes is low in absolute terms and when compared with the reduction in cardiovascular events achieved by treatment. In other words, the potential benefits to health are believed to outweigh potential … Read more
Today was a big day at the annual conference of the American Heart Association in Chicago. The results of the long and eagerly awaited IMPROVE-IT trial were presented. You may think IMPROVE-IT is just another ordinary study of the efficacy of a particular cholesterol lowering drug. But it’s more than that because it tests the important and heavily debated lipid … Read more
High-density lipoprotein cholesterol (HDL cholesterol) is commonly measured to assess the risk of heart disease. If you’ve had a blood sample drawn for assessment of lipid panel you probably already know if your cholesterol level is acceptable or not. You might also recall something about good and bad cholesterol and the ratio between these two. Of course, … Read more
Current medical knowledge is to a large extent based on results from scientific studies. Traditionally, these results are published in peer-reviewed medical journals. Before being accepted, a scientific paper has to go through critical assessment by expert reviewers who will assess the paper’s suitability for publication. The peer review process is intended to guarantee standards of quality and … Read more