Why and How To Lower Triglycerides in People at Risk of Heart Disease

Triglycerides are important organic compounds. Most of the fat we consume in our diet is triglyceride and so is most of the fat we store in our body. Fatty acids contained in triglycerides are an essential source of energy for the cells of our body. Triglyceride concentration can be measured in blood and may provide … Read more

The Fate of the PURE Study – Fat and Carbohydrate Intake Revisited

Most experts agree that diet is an important modifiable risk factor for cardiovascular disease and many other chronic noncommunicable disorders. Hence, defining and implementing a healthy diet is a matter of great public health interest. However, although there is substantial agreement on many issues, such as the importance of fruits and vegetables, several matters are still … Read more

Why LDL-Cholesterol May Be Overestimated on a Low-Carb, High-Fat (LCHF) Diet

Elevated LDL-cholesterol (LDL-C) is common among people who adopt a low-carb, high-fat (LCHF) lifestyle. That’s why many physicians and nutritionists remain doubtful when it comes to LCHF, despite overwhelming evidence that such a dietary approach improves several other lipid parameters, usually leads to weight loss and positively affects glucose metabolism. Several studies have shown that LDL-C constitutes a major risk factor for the … Read more

Fructose Restriction – An Effective Lipid Intervention?

Fructose Restriction – An Effective Lipid Intervention?

The association between lipid disorders and heart disease is well known. Medical checkups usually involve measurements of cholesterol and other lipid parameters, and most doctors advise their patients on how to improve their lipid pattern. Dietary interventions to lower the risk of heart disease commonly aim at reducing blood levels of cholesterol, LDL cholesterol in particular. This is … Read more

Low-Density Lipoprotein (LDL) in Atherosclerosis and Heart Disease

The death rate from coronary artery disease (CAD) has declined considerably over the last three decades, mostly because of better control of risk factors and advances in therapy. However, due to the aging of the population and better survival of those affected, the prevalence of the disease remains high. The current epidemic of obesity and type 2 diabetes will likely escalate the problem further. Atherosclerosis, … Read more

Low-Carb Diet to Treat Non-Alcoholic Fatty Liver Disease – Does It Make Sense?

Approximately 30 percent of people in the United States have a disease that is characterized by abnormal deposits of fat in the liver. The disease is not contagious, and unlike many other disorders of the liver, it is not caused by overconsumption of alcohol. It is called non-alcoholic fatty liver disease (NAFLD) and has become the leading cause of chronic liver disease … Read more

Sugar In and Sugar Out: The Modern Treatment of Type 2 Diabetes

A few days ago the results of a potentially game-changing trial on the treatment of type 2 diabetes and cardiovascular disease (EMPA-REG OUTCOME trial) were presented at an international diabetes conference in Stockholm, Sweden and simultaneously published in the New England Journal of Medicine (1). For the first time, a study has found that a drug that … Read more

Less Heart Disease Despite More Diabetes; The Role of Diet

The diverging trends in heart disease and diabetes represent a public health paradox of immense importance. Obesity and type 2 diabetes are well-known risk factors for coronary heart disease. However, whereas the prevalence of obesity and type 2 diabetes is increasing, the death rate from coronary heart disease is declining. This interesting paradox was recently addressed in two … Read more