Because Good Medicine Deserves Better Explanations
Author’s Note: This article was initially published in 2014. Since then, a growing body of research has strengthened the case for using the triglyceride-to-HDL cholesterol (TG/HDL-C) ratio as a simple, powerful marker of cardiometabolic risk. This 2025 update brings new clinical insight, clearer explanations, and a narrative approach to help readers understand why this ratio … Read more
An important question in clinical medicine is when to treat descending testosterone levels in men when there is no underlying cause other than advanced age. Most men want to live to a ripe old age. But this could come at a price. We may have to depart with masculinity and vigor. Manliness may become a … Read more
Polycystic ovary syndrome (PCOS) is a common disorder among women. It is characterized by menstrual irregularities, infertility, signs of androgen excess, and polycystic ovaries. It is often associated with obesity, insulin resistance, and lipid abnormalities. PCOS is the most common cause of infertility in women (1). PCOS was first described in 1934 by Irving F. Stein … Read more
More than eight million people in the U.S., almost 4% of the population, are estimated to suffer from gout. The disease often causes severe pain and physical disability. Gout is associated with increased blood levels of uric acid, called hyperuricemia. Uric acid is a biochemical substance the body has to deal with through our lifetime. It is an end … Read more
Knowing the role of VLDL (very low-density lipoprotein) and chylomicrons is a key factor in understanding how lipids (fats) and lipoproteins are involved in atherosclerotic cardiovascular disease (ASCVD). In the current era of adiposity and metabolic disease, VLDL has gained a bigger role than before and may help explain many of the disorders associated with the obesity epidemic such … Read more