The Triglyceride/HDL Cholesterol Ratio

The TG/HDL-C Ratio in Clinical Context For decades, cholesterol has been the headline act in our understanding of heart disease. High LDL-cholesterol (LDL-C) — the so-called “bad” cholesterol — was cast as the main villain, while HDL-cholesterol (HDL-C) earned praise as the “good” kind. Statins became the blockbuster therapy, and LDL-C targets the cornerstone of … Read more

The Difference Between LDL-Cholesterol (LDL-C) and LDL Particle Number(LDL-P)

The role of low-density lipoprotein cholesterol (LDL-C) in the evolution of heart disease is fairly well established. In addition, the benefits of pharmacological treatment with agents that lower LDL-C in high-risk patients are well documented. Lipoproteins are biochemical structures that enable the transport of lipids such as cholesterol in the circulation. LDL-C represents the amount … Read more

Non-HDL Cholesterol (non-HDL-C)

Non-HDL cholesterol (non-HDL-C) is a fraction that can be easily calculated from a traditional lipid panel. The value is strongly associated with an increased risk of heart disease. Over the years, LDL cholesterol (LDL-C) has been the most commonly used lipid variable to predict risk (1). However, current evidence suggests that non-HDL cholesterol may be … Read more

LDL-Cholesterol – The “Bad” Cholesterol Explained

There are several reasons why we should be interested in the amount of cholesterol circulating in our bloodstream. However, to interpret our cholesterol numbers, we have to know certain things about cholesterol and its role in health and disease.   What Is Cholesterol? Cholesterol is classified as a sterol (a combination of steroid and alcohol) … Read more