Because Good Medicine Deserves Better Explanations
At first, they were diabetes drugs.
GLP-1 receptor agonists—liraglutide, semaglutide, and later tirzepatide—were developed to help patients with type 2 diabetes regulate blood sugar. They mimicked a gut hormone, GLP-1, that modulates insulin, glucagon, and gastric emptying. They also acted on the brain.
Appetite went down.
Weight came off.
And people noticed.
A forgotten folder. A cryptic label. And a quiet set of instructions that may have rewritten the rules of modern medicine. This story doesn’t start with a discovery—it begins with a cover-up. Not in a lab or at a press conference, but deep in the shadows, in an archive no one was supposed to search. … Read more
In the summer of 1921, in a dim and dusty laboratory at the University of Toronto, a young surgeon with failing prospects and a second-year medical student began tying off the pancreatic ducts of dogs. What they were after was elusive—unseen, unnamed, and possibly imaginary. What they found would change the fate of millions. They … Read more
Our human ancestors had different food habits than we do. They did not routinely eat two to three regularly spaced, large meals every day. Indeed, food was often scarce, and there may have been long periods between meals. Furthermore, through the ages, fasting has been practiced in many communities for cultural and religious purposes. As … Read more
“Fatigue is here, in my body, in my legs and eyes. That is what gets you in the end. Faith is only a word, embroidered.” ― Margaret Atwood, The Handmaid’s Tale. Fatigue or tiredness is a common medical complaint that may seriously affect people’s quality of life. However, despite many possible underlying causes, a specific medical disorder is seldom … Read more