The Health Benefits and Risks of Physical Activity, Exercise, and Fitness
“Lack of activity destroys the good condition of every human being, while movement and methodical physical exercise save it and preserve it.” … Read more
Acute Myocardial Infarction
The CANTOS Trial – Is Targeting Inflammation the Solution to Heart Disease?
The recently published results of the long awaited CANTOS trial may forever change our approach to the prevention and treatment of coronary artery disease (1). Inescapably, there is now proof that targeting inflammation, in this case by a drug, significantly improves outcome for certain very high-risk patients. But, as so often in clinical research, things … Read more
17 Important Causes of Chest Pain
Chest pain is a common symptom associated with a variety of underlying causes. More than six million people visit hospital emergency departments in the United States each year because of chest pain (1). The cause of chest pain may vary from life-threatening conditions to those that are relatively harmless. Chest pain is most commonly caused by … Read more
Evolocumab (Repatha) for Heart Disease – The FOURIER Trial – Success or Failure?
The eagerly awaited results of the FOURIER trial were recently presented at the Annual Meeting of the American College of Cardiology (ACC) in Washington DC and simultaneously published in the New England Journal of Medicine (1). The goal of FOURIER was to evaluate the efficacy and safety of evolocumab (Repatha), a PCSK9 inhibitor, among subjects with elevated risk … Read more
Angina Pectoris – What Is Angina and How Do We Deal With It?
The term angina pectoris or angina is used to describe chest pain or discomfort, often felt like pressure or a squeezing sensation in the chest. The pain may radiate to the shoulders, arms, neck, jaw or the back region between the shoulder blades. Angina is not a disease. It is a symptom, usually caused by inadequate … Read more