Lipoprotein(a)

Measurements of lipids in blood/plasma are frequently used to assess the risk of future coronary heart disease or stroke, commonly termed cardiovascular disease (CVD). Plasma levels of total cholesterol, triglycerides and high density lipoprotein cholesterol (HDL-C) are frequently measured. These numbers are then used to calculate levels of low density lipoprotein cholesterol (LDL-C) which has been found … Read more

Low Carb Diets and Heart Disease – What Are We Afraid of?

I find it extraordinary how carbohydrate restriction is repeatedly rejected by the medical community as an alternative approach for obesity, the metabolic syndrome and type 2 diabetes. Obesity has reached epidemic proportions in many countries around the world. Diabetes and other obesity related disorders have become increasingly common. Public health organizations and medical societies usually … Read more

What Is the Best Diet for Type 2 Diabetes?

An interesting scientific paper on the efficacy of different dietary approaches in type 2 diabetes recently caught my eye. The study has not received much media coverage although it certainly addresses a question of importance to millions of people worldwide. More than 20 million people in the US have type 2 diabetes. According to the … Read more

Diet or Drugs to Prevent Heart Disease

The risk of heart disease has been associated with countless different things. Smoking, diabetes, high blood pressure, overweight, obesity, sitting and watching TV, eating too much fat, eating too much sugar, not eating certain fats, eating meat, not eating fish, eating too much animal fat, eating cholesterol, eating saturated fat, eating trans fats, high blood … Read more

Dietary Fats and Heart Disease – Exposing the Villain

“I would only argue that Senators don’t have the luxury that the research scientist does, of waiting until every last shred of evidence is in.” These words were spoken by Senator George McGovern 35 years ago when confronted by Dr. Robert Olson from St. Louis University. Senator McGovern’s Select Committee on Nutrition and Human Needs … Read more

Exploring “The Great Cholesterol Myth”

I have a strong interest in the prevention of heart disease. I believe healthy nutrition and lifestyle are the keys to our health and well-being. In my early career as a cardiologist, working in the hospital setting, I was fascinated by the diagnosis and treatment of heart disease. Don’t misunderstand me, I still am. However, as the … Read more

Statins – Friend or Foe?

Last year I wrote a couple of articles about statin therapy, so maybe you think I should give it a rest. However, I think it is such a hugely important issue, and I have this strong feeling that the truth really has not emerged yet. Firstly, two recent scientific papers touching on the effects of … Read more

The Difference Between LDL-C and LDL-P

The lipid hypothesis, suggesting a causative role for cholesterol in atherosclerotic heart disease is by many considered one of the best proven hypotheses in modern medicine. Measurements of total cholesterol, and the amount of cholesterol bound to different lipoproteins, are commonly used to assess the risk of future cardiovascular events. However, recent research into the role … Read more

Apolipoprotein B (apoB)

Atherosclerosis may be described as a chronic inflammation in the arterial wall. It is caused by a complex interplay between lipoproteins, white blood cells (macrophages), the immune system and the normal elements of the arterial wall. This process leads to formations of atherosclerotic lesions or plaques that may protrude into the lumen of the artery … Read more

PCSK9

These are exciting times for the field of cardiovascular medicine. Despite huge improvements in risk factor modification and progress in medical and surgical therapy, cardiovascular disease remains the most frequent cause of death among most nations. However, increased understanding of the mechanisms behind atherosclerosis, the role of lipoproteins, inflammation and other factors, has opened gates to … Read more