Using Coronary Calcium Score to Target Statin Treatment in Primary Prevention – The Biolmage Study

Cholesterol-lowering medications are being prescribed to almost 30% of US adults aged 40 and over, most of these are statins drugs (1). The number increases with age, and approximately 48% of adults older than 75 are receiving such treatment. It has been suggested that treating more older individuals with statins may prevent a substantial number of cardiovascular events, and that, … Read more

GLAGOV – The Lipid Hypothesis Gains Ground

The results from the recent GLAGOV trial suggest that aggressive lowering of LDL-cholesterol with a PCSK9-inhibitor on top of statin therapy in patients with coronary artery disease may reduce atherosclerotic plaque burden. Although these results provide support for the lipid hypothesis and may have significant implications for the future of cardiovascular medicine, our eyes are still on safety and … Read more

Weight Management – The Role of Exercise Revisited

In the midst of the obesity epidemic, one of our most important concerns is the association between body mass index (BMI) and the risk of cardiovascular disease (CVD). However, body weight itself may not be what matters most. Evidence suggests that obesity measures such as BMI, waist circumference, or waist-to-hip ratio, assessed singly or in combination, … Read more

Swollen Feet and Swollen Ankles – Leg Edema Explained

Swollen feet and swollen ankles are common reasons why people seek medical advice. I’m not talking about inflammation due to injury or infection, but a medical condition commonly called leg edema. Leg edema is not only undesirable due to cosmetic reasons but may lead to thinning of the skin, discoloration or staining (pigmentation) and skin sores (ulcers). Healing may be … Read more