Melatonin – 15 Questions and Answers About Melatonin and Sleep

Melatonin is a hormone that regulates sleep, wakefulness, and circadian rhythms in humans. Circadian rhythm describes the sleep/wake cycle, a biological clock that runs in our brain and cycles between sleepiness and alertness. It explains why we may feel energized or sleepy at around the same time each day. We all know that sleep is crucial … Read more

10 Important Symptoms of Depression

Major depression affects more than 16 million American adults each year (1). It can occur to anyone, at any age. And, importantly, depression is not a personal weakness but a severe medical illness. Of course, we all have times when our mood is low. Gloom, heartache, melancholy, woe, desolation. These are all parts of life’s … Read more

Exploring the “Lore of Nutrition”

For the last few days, my Kindle has been my closest companion. “What are you reading”? my wife asked. “I’m reading Lore of Nutrition.” “Ooh, I was sure it was a thriller or one of your crime stories.” In fact, she was right. Although Lore of Nutrition is a book about nutrition, it reads like … Read more

19 Important Causes of Fatigue – Tiredness and Chronic Fatigue Explained

“Fatigue is here, in my body, in my legs and eyes. That is what gets you in the end. Faith is only a word, embroidered.”  ― Margaret Atwood, The Handmaid’s Tale. Fatigue or tiredness is a common medical complaint that may seriously affect people’s quality of life. However, despite many possible underlying causes, a specific medical disorder is … Read more

The Fate of the PURE Study – Fat and Carbohydrate Intake Revisited

Most experts agree that diet is an important modifiable risk factor for cardiovascular disease and many other chronic noncommunicable disorders. Hence, defining and implementing a healthy diet is a matter of great public health interest. However, although there is substantial agreement on many issues, such as the importance of fruits and vegetables, several matters are still … Read more

Muscular Strength and Longevity – The Role of Strength Training

In 1953, British researchers discovered that drivers of London’s double-decker buses were more likely to suffer a deadly heart attack than the more physically active conductors (1). Another study published five years later found that the risk of heart attack was higher among government clerks than postmen (2). These studies laid the foundation for the hypothesis … Read more

25 Important Causes of Stomach Pain – Understanding Abdominal Pain

Stomach pain, also known as abdominal pain, is caused by a variety of conditions most of whom are innocent or benign. However, sometimes, abdominal pain may be due to a severe disorder needing immediate intervention. The abdomen is the part of the body between the thorax (chest) and the pelvis. Other common names used to describe … Read more

The CANTOS Trial – Is Targeting Inflammation the Solution to Heart Disease?

The recently published results of the long awaited CANTOS trial may forever change our approach to the prevention and treatment of coronary artery disease (1). Inescapably, there is now proof that targeting inflammation, in this case by a drug, significantly improves outcome for certain very high-risk patients. But, as so often in clinical research, things … Read more