The Triglyceride/HDL Cholesterol Ratio

The TG/HDL-C Ratio in Clinical Context For decades, cholesterol has been the headline act in our understanding of heart disease. High LDL-cholesterol (LDL-C) — the so-called “bad” cholesterol — was cast as the main villain, while HDL-cholesterol (HDL-C) earned praise as the “good” kind. Statins became the blockbuster therapy, and LDL-C targets the cornerstone of … Read more

The Explorer Who Ate Only Meat—and Lived to Tell the Tale

In the winter of 1906, somewhere north of the Arctic Circle, a young explorer named Vilhjalmur Stefansson sat cross-legged in an igloo, surrounded by Inuit hunters. Outside, the wind cut like a knife, shrieking across the frozen plain. Inside, the flickering light of seal oil lamps cast dancing shadows on the snow-packed walls. The air … Read more

Non-HDL Cholesterol (non-HDL-C)

Non-HDL cholesterol (non-HDL-C) is a fraction that can be easily calculated from a traditional lipid panel. The value is strongly associated with an increased risk of heart disease. Over the years, LDL cholesterol (LDL-C) has been the most commonly used lipid variable to predict risk (1). However, current evidence suggests that non-HDL cholesterol may be … Read more