HbA1c and Diabetes – Glycated Hemoglobin (A1c) Explained

Diabetes and its complications remain a major cause of early disease and death worldwide. The diagnosis of diabetes is to a large extent based on detecting elevated levels of sugar (glucose) in the blood. Blood sugar levels can easily be measured at home with a glucometer. Hemoglobin A1c (HbA1c) is another laboratory measure frequently used for this … Read more

Nonalcoholic Fatty Liver Disease (NAFLD) – Fatty Liver Explained

Recently, non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease in the United States and other Western countries. The prevalence of the disorder is estimated to be as high as 30% in the general population (1). With obesity being a major risk factor and due to the aging of the population, the … Read more

Metabolic Syndrome and Insulin Resistance

The metabolic syndrome is a constellation of risk factors, most usually associated with increased body weight, fat accumulation around the abdominal organs often termed central, or visceral obesity (1), and increased resistance to the effects of insulin. Other names that have been used to describe the metabolic syndrome are syndrome X, the insulin resistance syndrome, the deadly quartet (2) and … Read more

Cholesterol and Heart Disease – A Quick Look Beyond

The word cholesterol is inherent to heart disease. Just like Paris is the capital of France and the Moon orbits the Earth, so cholesterol is associated with heart disease. And common knowledge extends further. Most people know that cholesterol is measured in blood and that there’s is supposed to be both good and bad cholesterol. Bad cholesterol may … Read more

Dietary Fat, Carbohydrates and Metabolic Syndrome

Time makes us fat. It’s not a myth, it’s a biologic fact. When we get old we get fat. In December 1863, William Banting, an English undertaker who went to great lengths to treat his own obesity, wrote in his now famous Letter on Corpulence: … For I have been generally informed that corpulence is one of the natural results of … Read more

The Modern-Day Heart Patient – From One Risk Profile to Another

Although the death rate from coronary heart disease (CHD) has declined rapidly during the last few decades, CHD remains the most common cause of death in most countries around the world. The reduction in death rate is partly due to fewer people being diagnosed with CHD and partly due to a better prognosis of those … Read more

10 Pitfalls of Using LDL Cholesterol to Assess Risk

Blood levels of low-density lipoprotein cholesterol (LDL-C), commonly termed the “bad cholesterol” are widely used to assess the risk of future heart disease. A traditional lipid panel measures total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-C). These numbers are then used to calculate LDL-C which has been found to be strongly correlated with the risk of cardiovascular disease … Read more

Taxing Animal Fat Is Necessary – Still Chasing the Usual Suspects

New Nordic/Scandinavian public recommendations on diet and nutrition will be published this autumn. According to an article (English version-Google translation) published in a Swedish newspaper last week the new guidelines will underscore the risks of animal-derived saturated fats. The article is written by three Swedes, two of whom are experts in the field of health and nutrition. … Read more

10 Scientific Facts About Diet and Inflammation

Most of us realize that lifestyle plays a profound role in many of the chronic diseases of modern society. Despite our knowledge, it seems that somewhere along the path we have gone astray. Body weight is on the rise and people are becoming more sedentary. Obesity, the metabolic syndrome, and type-2 diabetes are becoming public … Read more