Bempedoic Acid – A New Treatment Alternative for Statin Intolerant Patients?

Statin drugs play an important role in the treatment of cardiovascular disease and have been shown to improve the prognosis of patients with established atherosclerotic heart disease. Statins, however,  are not without side effects, and 7 to 29% of patients report adverse musculoskeletal effects that limit their ability to use them as recommended by clinical … Read more

Do COVID-19 Vaccinations Reduce the Risk of Heart Conditions Following Covid-19 Infections?

A hugely important question for the clinical cardiologist is whether Covid-19 vaccinations reduce the risk of cardiovascular complications following Covid-19 infections. It is well-documented that being infected with SARS-CoV-2 increases the risk of short-and long-term cardiovascular complications, many of which may be severe. Therefore, practicing clinicians and patients will embrace every tool that can be … Read more

Intermittent Fasting and Health – What’s the Scientific Evidence?

Our human ancestors had different food habits than we do. They did not routinely eat two to three regularly spaced, large meals every day. Indeed, food was often scarce, and there may have been long periods between meals. Furthermore, through the ages, fasting has been practiced in many communities for cultural and religious purposes. As … Read more

Atherogenic Dyslipidemia (AD)

Atherogenic dyslipidemia (AD) is a clinical disorder that, in my opinion, is far too often overlooked.  It depicts a blood lipid pattern characterized by elevated triglycerides (TG) and low levels of high-density lipoprotein cholesterol (HDL-C). Hence, people with AD have an elevated TG/HDL-C ratio (1). More crucially, individuals with AD have elevated apolipoprotein B (apoB) … Read more

The Difference Between LDL-Cholesterol (LDL-C) and LDL Particle Number(LDL-P)

The role of low-density lipoprotein cholesterol (LDL-C) in the evolution of heart disease is fairly well established. In addition, the benefits of pharmacological treatment with agents that lower LDL-C in high-risk patients are well documented. Lipoproteins are biochemical structures that enable the transport of lipids such as cholesterol in the circulation. LDL-C represents the amount … Read more