Because Good Medicine Deserves Better Explanations
“The physician must learn to bear the wounds of the heart.”— Ambroise Paré I used to think I could stay untouched by the pain I witnessed. That I could carry grief without absorbing it. That I could walk through medicine without it ever walking through me. No one practices medicine for long without being … Read more
Author’s note (2025 update) This article was originally published in 2017 and revised in 2021. It has now been updated and expanded for 2025 to include new clinical insights, refined explanations, and additional causes of chest pain. Chest pain is one of the most common—and most alarming—symptoms in medicine.In the United States, millions of people … Read more
He sits across from me, his file glowing on the computer screen. Numbers everywhere: cholesterol edging upward, blood pressure leaning north, a family tree littered with cardiac potholes.
He leans forward, eyes narrowing.
“So, doctor—what are my chances?”
I recite the liturgy: statins cut relative risk by about 25%, blood pressure control lowers stroke risk by 30–40%. Add them up, and the curves bend favorably.
He doesn’t look reassured.
“Yes, but will it happen to me—or not?”
The room is silent except for the tick of the wall clock. A man lies in a hospital bed, motionless beneath starched white sheets.His hair is slicked back, his slippers placed neatly on the floor.His face is pale, but his eyes are quietly alert — not fearful, exactly, but watchful, as if trying to read … Read more
At first, they were diabetes drugs.
GLP-1 receptor agonists—liraglutide, semaglutide, and later tirzepatide—were developed to help patients with type 2 diabetes regulate blood sugar. They mimicked a gut hormone, GLP-1, that modulates insulin, glucagon, and gastric emptying. They also acted on the brain.
Appetite went down.
Weight came off.
And people noticed.