Because Good Medicine Deserves Better Explanations
At first, they were diabetes drugs.
GLP-1 receptor agonists—liraglutide, semaglutide, and later tirzepatide—were developed to help patients with type 2 diabetes regulate blood sugar. They mimicked a gut hormone, GLP-1, that modulates insulin, glucagon, and gastric emptying. They also acted on the brain.
Appetite went down.
Weight came off.
And people noticed.
The sirens were still wailing as the limousine skidded to a halt at Parkland Hospital. Secret Service agents leapt out, blood on their sleeves, shouting for help. A stretcher rattled through the emergency doors with the President’s broken body. Moments later, from another car in the motorcade, came his doctor. George Gregory Burkley walked quickly … Read more
We’ve become a society defined by distraction, acceleration, and mental erosion. The fog isn’t a glitch. It’s the weather report.
Not long ago, I saw a 58-year-old man who had done “everything right.” His LDL cholesterol (LDL-C) was well controlled on a statin, his blood pressure stable, and he exercised regularly. But he carried extra weight around his waist, his triglycerides were persistently high, and a CT scan revealed clear signs of atherosclerosis in his … Read more
He knew it was coming. The way a storm announces itself in the bones.The way a man knows the land he’ll die on. Lyndon Baines Johnson had already faced the thing most men spend their lives avoiding: death. It had gripped his chest, dropped him to the bedroom floor of his Texas ranch, and whispered … Read more